Our platform is particularly useful in biomedical research and drug discovery in oncology (tumor vaccines, targeted cancer immunotherapy, CAR-T, and TCR-T cell therapy), autoimmunity (autoantigen discovery, targeted immune modulation, regulatory TCR-T cell therapy), and infectious diseases (vaccines, chronic infection). Its modular design additionally provides the platform with the flexibility to easily incorporate alternative antigen-presenting cells, scales of throughput, and multiplexing options. Whenever the specificity of a T cell response in patients is of interest, our technology can provide valuable new insights.